Open Coronary Artery Bypass Graft (CABG) Surgery

Article Links

Evaluation of PAS-PORT in CABG Surgery (EPIC)
The Journal of Thoracic and Cardiovascular Surgery

The Cardica C-Port System...
The Journal of Thoracic and Cardiovascular Surgery

Twelve Month Patency with the PAS-Port Proximal Connector Device
A Single Center Prospective Randomized Trial

Six-Month Angiographic Follow-Up of the PAS-Port II Clinical Trial
The Annals of Thoracic Surgery

Risk of Stroke With Coronary Artery Bypass Graft Surgery Compared With Percutaneous Coronary Intervention
Journal of the American College of Cardiology

More Scientific Literature

Off-Pump CABG

Off-Pump "Beating Heart" Coronary Artery Bypass Graft Surgery

Once thought impossible, cardiac surgeons can now perform coronary artery bypass graft (CABG) procedures while the heart is still beating. During a "beating heart" bypass procedure, a surgeon uses a heart stabilizer to reduce the movement in the area of the heart to be bypassed. Eliminating the use of the heart-lung machine reduces complications such as stroke, increased need for blood transfusions, and kidney and lung complications.

Research shows that beating heart CABG procedures improve patient outcomes for:

  • Women
  • Patients with carotid artery stenosis
  • Patients with prior stroke
  • Patients with compromised pulmonary or renal function

C-Port® Distal Anastomosis System (C-Port system) attaches the end of a bypass graft to a coronary artery downstream of an occlusion or narrowing during coronary artery bypass graft (CABG) surgery.

C-Port system:


"Works on very small coronary arteries."


  • Create compliant anastomoses that expand and contract with blood flow
  • Work on coronary arteries greater than 1.3 millimeters in internal diameter
  • Produce consistent, reproducible anastomoses, largely independent of surgical technique and skill set
  • Do not interrupt blood flow while the anastomosis is being completed
  • Allow mechanically-governed repeatability and reduced procedural complexity
  • Works with grafts of various diameters and target vessels that have single wall thicknesses less than or equal to 0.75 millimeters
  • Can be used on- or off-pump
  • Uses miniature stainless steel clips to secure the bypass graft to the coronary artery
  • Minimize scarring and potential occlusion of the anastomosis by achieving nearly complete alignment of the natural blood lining surfaces of the coronary artery and the graft

Graft Preparation
The bypass graft vessel in preparation for loading onto the
C-Port system.
Graft Secured
The graft is secured on the C-Port arm and is ready for deployment.
Vessel Loaded
The anastomosis is loaded onto the device, ready to be connected to the coronary artery.

To see more information on specific C-Port system:

A clinical study demonstrated that 95% of the graft vessels studied following an anastomosis with the C-Port device were found to be open in angiograms performed at 6 months postoperatively. To view this study, click here.

PAS-Port® Proximal Anastomosis System (PAS-Port system)

Our PAS-Port system is a fully-automated device used to perform an anastomosis between a saphenous vein and the aorta during either on- or off-pump CABG surgery. The PAS-Port system has been used in Japan and Europe since 2004, and received 510(k) clearance in the United States in 2008.

The PAS-Port system is designed to:


"Eliminate aortic clamping and manipulation."

  • Eliminate clamping, which may reduce the risk of particle release and ensuing neurocognitive events
  • Allow the surgeon to load the bypass graft and rapidly complete the anastomosis, typically in approximately one minute
  • Provide one-turn aortotomy and anastomosis
  • Reduce time required for anastomosis
  • Produce consistent, reproducible anastomoses, largely independent of surgical technique and skill set
  • Ensure secure graft attachment allowing for variable take-off angles
  • Leave no metal within the graft lumen
  • Be loaded into the system without damaging endothelial cells while maximizing the orifice, especially important in small grafts
  • Allow mechanically-governed repeatability and reduced procedural complexity

Pull Through
The bypass vessel graft is pulled through the PAS-Port system in preparation for deployment.
The graft vessel is everted in preparation for deployment.
Poke Through
The vessel is prepared and ready to attach to the aorta.

PAS-Port System Met All Endpoints in Pivotal Trial

A 220-patient, prospective, pivotal, randomized trial of the PAS-Port® system was conducted at 12 sites in the United States and Europe. The trial compared venous bypass grafts to the aorta made using the PAS-Port system versus those made using conventional hand-sewn sutures. Results showed that the study met its primary endpoint of non-inferiority to hand-sewn anastomoses, as well as all other primary and secondary endpoints.

The results of the EPIC trial have been published in the July 2009 issue of The Journal of Thoracic and Cardiovascular Surgery. To view this study, click here.

For more information about the products, please contact AesDex, LLC.



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