Open Coronary Artery Bypass Graft (CABG) Surgery

Article Links

Evaluation of PAS-PORT in CABG Surgery (EPIC)
The Journal of Thoracic and Cardiovascular Surgery.

The Cardica C-Port System
The Journal of Thoracic and Cardiovascular Surgery

On-Pump CABG

On-Pump Coronary Artery Bypass Graft Surgery

On-pump CABG surgery is performed by taking a small part of a blood vessel from another part of the body, usually a vein from the leg, for use as the graft vessel. In the majority of CABG procedures performed in the United States, the patient's heart is stopped temporarily while surgeons use a continuous thread to hand sew vessels together, bypassing the blockages. During this procedure, a mechanical cardiopulmonary bypass machine keeps the blood circulating through the body. The blood is rerouted through the healthy vessel and blood flow is restored to the heart muscle.

During on-pump CABG procedures, Cardica's automated products allow surgeons to use a much larger range of veins and arteries from very small diameter vessels to larger veins.

C-Port® Distal Anastomosis Systems (C-Port systems) attach the end of a bypass graft to a coronary artery downstream of an occlusion or narrowing during coronary artery bypass graft (CABG) surgery.

C-Port systems:


"Works on very small coronary arteries."

  • Create compliant anastomoses that expand and contract with blood flow
  • Work on coronary arteries as small as 1.25 millimeters in internal diameter
  • Produce consistent, reproducible anastomoses, largely independent of surgical technique and skill set
  • Do not interrupt blood flow while the anastomosis is being completed
  • Allow mechanically-governed repeatability and reduced procedural complexity
  • Work with grafts of various diameters and wall thicknesses less than 1.4 millimeters
  • Can be used on- or off-pump
  • Use miniature stainless steel staples to secure the bypass graft to the coronary artery
  • Minimize scarring and potential occlusion of the anastomosis by achieving nearly complete alignment of the natural blood lining surfaces of the coronary artery and the graft

Graft Preparation
The bypass graft vessel in preparation for loading onto the
C-Port system.
Graft Secured
The graft is secured on the C-Port arm and is ready for deployment.
Vessel Loaded
The anastomosis is loaded onto the device, ready to be connected to the coronary artery.

A clinical study demonstrated that 95% of the graft vessels studied following an anastomosis with the C-Port device were found to be open in angiograms performed at 6 months postoperatively. To view this study, click here.

To see more information on specific C-Port systems:

PAS-Port® Proximal Anastomosis System (PAS-Port system)
is a fully-automated device used to perform ananastomosis between a saphenous vein and the aorta during either on- or off-pump CABG surgery.

The PAS-Port system is designed to:

"Reduce time required for anastomosis, thereby reducing
on-pump time."

  • Provide one-turn aortotomy and anastomosis
  • Produce consistent, reproducible anastomoses, largely independent of surgical technique and skill set
  • Ensure secure graft attachment allowing for variable take-off angles
  • Leave no metal within the graft lumen
  • Allow the surgeon to load the bypass graft and rapidly complete the anastomosis, typically in approximately one minute
  • Be loaded into the system without damaging endothelial cells while maximizing the orifice, especially important in small grafts

Pull Through
The bypass vessel graft is pulled through the PAS-Port system in preparation for deployment.
The graft vessel is everted in preparation for deployment.
Poke Through
The vessel is prepared and ready to attach to the aorta.

PAS-Port System Met All Endpoints in Pivotal Trial

AesDex, LLC conducted a 220-patient, prospective, pivotal, randomized trial of the PAS-Port® system at 12 sites in the United States and Europe. The trial compared venous bypass grafts to the aorta made using the PAS-Port system versus those made using conventional hand-sewn sutures. Results showed that the study met its primary endpoint of non-inferiority to hand-sewn anastomoses, as well as all other primary and secondary endpoints.

The results of the EPIC trial have been published in the July 2009 issue of The Journal of Thoracic & Cardiovascular Surgery. To view this study, click here.

For more information about AesDex products, please contact sales.


With the acquisition of Dextera Surgical's assets, Cardica products are now manufactured by AesDex, LLC, and distributed by Aesculap.
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AesDex's stapling technology is designed to minimize operating time and to enable minimally-invasive and robot-assisted surgeries.
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